Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. Outcomes for mucous membrane pemphigoid depend on early. Mucous membrane pemphigoid mmp is a rare autoimmune bullous disease of the mucous membranes, which can cause irreversible scarring and is discussed to be associated with cancer, if laminin332. Mucous membrane pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Abstract lichen planus pemphigoides lpp is a rare autoimmune subepidermal blistering disease characterized by the coexistence of both lichen planus and bullous pemphigoid or mucous membrane pemph. Mucous membrane pemphigoid is a rare autoimmune blistering disease primarily affecting mucosal surfaces. Like other forms of pemphigoid, the disorder is characterized by the formation of autoantibodies against structural proteins of the dermalepidermal junction. Scarring can result in severe structural changes to the vulva that may mimic the. Other diseases that produce the latter pattern linear band on. If it involves the deeper parts of the throat, it may cause respiratory compromise. Mucous membrane pemphigoid mmp this form of the disease affects the eyes, mouth, and throat. Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial blisters. Other names include cicatricial pemphigoid, oral pemphigoid and ocular pemphigoid. Treatment strategies in mucous membrane pemphigoid article pdf available in therapeutics and clinical risk management 43.
Various basement membrane zone components have been identified as targets of. A clinical formocular cicatricial pemphigoid ocpmay result in blindness if it involves the eyes. Other moist surfaces of the body known as mucous membranes can. Various basement membrane zone components have been identified as targets of autoantibodies in mmp and the disease is characterised by dermatologists based on these components. Mmp is an uncommon blistering conditionwhich most frequently affects the lining of the mouth and gums. Report of two cases of mucous membrane pemphigoid with. Bullous pemphigoid bp this strain is limited to the skin. Mucous membrane pemphigoid is a heterogeneous subepithelial blistering disease that predominantly affects the mucous membranes, including the conjunctiva and occasionally the skin. Pdf treatment strategies in mucous membrane pemphigoid.
659 932 849 1550 613 1082 898 1243 399 302 1406 442 1195 491 1357 1438 335 746 294 1059 446 9 1204 204 1009 946 291 1181 30 328 25 1018 938 734 1594 268 1018 138 450 885 1427 145 1011 204 129 924 1140